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5-HTP (5-Hydroxytryptophan)
is a safe, a natural treatment for weight loss, anxiety, depression, migraines, addiction, and an effective antidepressant.  Regulates brain serotonin levels. Promote natural nutritional support for your mental and emotional well-being with  5-HTP! This unique extract from griffonia seeds works naturally within the body to promote healthy levels of serotonin, a hormone that helps regulate mood and sleep patterns.

Research indicates 5-HTP may:*

  • Help with sleep cycles
  • Help control appetite
  • Support a healthy mood
  • Calm mild Anxiety
  • Ease migraine pain


Ingredients L-5 HTP  100 mg
other ingredients: Rice flour, Geletin
Suggested Use:  As a dietary supplement, take on capsule one to two times per day with water on an empty stomach.

  General Description
L-5-Hydroxytryptophan, or 5-HTP, (also called L-5-hydroxytryptophan or levo-5-hydroxytryptophan) is a natural compound manufactured in the body as a metabolite of L-tryptophan, an amino acid found in a variety of dietary proteins. Supplemental 5-HTP is derived from the seeds of the West African medicinal plant Griffonia simplicifolia

Health applications

  • Depression
  • Insomnia
  • Fibromyalgia
  • Migraine headaches
  • Weight loss/obesity

Primary functions
The body uses 5-HTP to produce serotonin, a neurotransmitter involved in sleep, moods, appetite, pain control, and other body functions. Because 5-HTP is inactive in the body until it is converted into serotonin, the physiological effects of 5-HTP supplementation depend upon its ability to increase serotonin production.

Because alterations in serotonin metabolism appear to be an important factor in the development of depression, researchers have been investigating the therapeutic potential of 5-HTP in depressed patients. Preliminary trials indicate that 5-HTP may help improve symptoms in some forms of depression,1-4 with the best results obtained in patients with anxious-agitated depressive syndromes and patients with acute endogenous depression.4 While these small-scale studies show promise, larger, long-term trials are needed to confirm their results.

Scientists have observed low serum serotonin levels in patients with fibromyalgia, compared to healthy controls.5,6 Studies indicate that supplemental 5-HTP may improve symptoms (including depression, anxiety, insomnia, number of tender points, pain intensity, and fatigue) in many fibromyalgia patients,7-9 presumably by increasing serum serotonin levels.

Migraine headaches
Abnormal serotonin metabolism has been implicated in the development of migraine headaches,10,11 suggesting a possible role for 5-HTP in migraine therapy. Clinical trials have shown 5-HTP to be effective in reducing the frequency12-14 and severity12-15 of migraine attacks in some subjects. Although 5-HTP was less effective than some other migraine treatments,13,15 its relatively low incidence of side effects (which were generally mild and transient 14) suggests it could be useful for individuals sensitive to other migraine medications.

Because serotonin is believed to play a significant role in sleep patterns, it has been suggested that increasing serotonin levels by supplementing serotonin precursors such as L-tryptophan and 5-HTP may improve sleep in some insomniacs. In the 1980s, tryptophan supplements gained popularity as natural sleep aids, and several studies showed improved sleep latency (the time it takes to fall asleep) in insomniacs given L-tryptophan.16-22 Presumably, 5-HTP would have a similar effect because L-tryptophan must be converted into 5-HTP before it can be reduced to serotonin. However, large-scale studies on the efficacy of 5-HTP in treating insomnia are lacking.

Weight loss
Investigations into the role of neurotransmitters in regulating appetite suggest 5-HTP may be an effective weight-loss aid. Placebo-controlled trials showed significant weight loss and reduction of carbohydrate intake in obese subjects given 5-HTP.23-25 The efficacy of 5-HTP in promoting weight loss in nonobese subjects has not been demonstrated.

Doses of 5-HTP used in clinical trials have ranged from 100-400 mg/day for migraine to 900 mg/day for weight loss, and this dosage range appears to be safe for most people. Reported side-effects, including gastrointestinal upset, headache, sleepiness, and anxiety, are usually mild. 5-HTP may produce harmful interactions with some drugs, including many antidepressants and appetite suppressants. People taking antidepressants or other prescription medications should consult a physician before using 5-HTP.

More Information about 5 HTP



**For your information: The products and the claims made about specific products on or through this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.*

Since 1998 
All rights reserved
  by Bonnie Dare


Add to Cart 
5-Hydroxy L-Tryptophan (5-HTP)100 mg
120 Veggie caps

Supplement your nutrition and health knowledge with timely news and research Information to help you find the answers to address your immediate health concerns. Great Information about  herbs, and how they affect your health, and what diet herbal supplement is used for which ailment.

* RDA means the Recommended Daily Allowance established by the U.S. Food and Drug Administration. This is the minimum daily amounts of specific essential nutrients necessary for healthy adults 18 year of age. Requirements increase with age and the RDA may be insufficient for older adults or those with poor health.*

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